Dental News - Columbia University announces break-through in tooth regeneration

Daniel Zimmermann, DTI

Wed. 26 May 2010

save

NEW YORK, USA/LEIPZIG, Germany: Dental implants could soon become a secondary choice for replacing natural teeth. According to new research from the College of Dental Medicine at Columbia University in New York, three-dimensional scaffolds infused with stem cells could yield an anatomically correct tooth in as soon as nine weeks once implanted. The new technique, developed by Columbia University professor Jeremy Mao, has also shown potential to regenerate periodontal ligaments and alveolar bone, which could make way to re-grow natural teeth that fully integrate into the surrounding tissue.

Previous research on tooth regeneration has been focusing on harvesting stem cells directly on dental implants to improve osseointegration or outside the body where the tooth is grown under laboratory conditions and implanted once it has matured. Mao’s technique, which has been tested on animal-models, is moving the harvesting process directly into the socket where the tooth can be grown ‘orthotopically’.

“A key consideration in tooth regeneration is finding a cost-effective approach that can translate into therapies for patients who cannot afford or who aren’t good candidates for dental implants,” Dr Mao told Dental Tribune Asia Pacific. “Our findings represent the first report of regeneration of anatomically shaped tooth-like structures in vivo.”

Dr Mao’s study has been published in the recent Journal of Dental Research and will be presented at this year’s International Association of Dental Research congress in Barcelona. Columbia has also announced to have filed patient applications in relation to the engineered tooth and is actively seeking partners to help commercialise the technology through its technology transfer office Columbia Technology Ventures.

21 thoughts on “Columbia University announces break-through in tooth regeneration”

Joy Distad says:

August 10, 2022 at 1:06 am

This could potentially save lives, including mine. This is hope to us, that suffer with teeth loss and or pain issues by oral health. Teeth are critical for nourishment. Teeth effect total body including mental health. This is amazing news to me. I pray I will live, here on earth, to see this as an opportunity for myself.
I would appreciate being in any trial for this or being a patient to receive stem cell regeneration of teeth.
harleydave says:

August 30, 2021 at 6:33 am

how would this process work on a patient with a loss of bone mass?? i have bone mass loss to the point that i am unable to get traditional implants. is there any hope for me to take part in this dream?? thanks
Lula Holmes says:

July 13, 2021 at 5:48 am

I would like to be part of the clinical trials
Robert Baker says:

June 30, 2021 at 4:10 am

When & where can I get it done ✅
Crystal says:

June 1, 2021 at 10:55 pm

Where do I sign up …my location ( Spain )
Isabelle says:

May 19, 2021 at 9:19 pm

Does this also work for only tooth enamel?
Sandra Ore says:

April 15, 2021 at 8:01 pm

Hello,

Is there an update on the commercialization of this procedure – the regrowth of teeth through stem cells at Columbia University College of Dental Medicine? Have family that are interested and would benefit from it. Please do respond.
Lana McLean says:

December 2, 2020 at 2:41 am

I live in Australia and I would like to register as a volunteer for any human trials in Australia (Melbourne)
Chad Zelasney says:

October 18, 2020 at 1:24 am

I’m very interested in this as I’m not a good candidate for regular dentistry.
Evens says:

September 22, 2020 at 4:11 pm

Where can I get this done please.
Hannah says:

January 6, 2020 at 4:27 pm

Where and how do I sign up ?
Syed Farhan says:

December 7, 2019 at 12:56 am

If you need a volunteer for regrowing teeth i’m interested to co-operat.
Kamila says:

October 12, 2019 at 8:37 pm

Chcę zapytać czy mogę odnowić zęby. Proszę o kontakt. Pozdrawiam
Carolyn says:

September 1, 2019 at 4:47 am

I would love to get my teeth regrown. My son has two that need to be regrown
Carolyn Ricker says:

September 1, 2019 at 4:41 am

Where can we get this done? My son has two teeth that need to be regrown.
Juanita Mejia says:

August 16, 2019 at 9:50 pm

Where can I get this done , l live in New York City and I would love to volunteer in regrowing your own teeth and bone. When can I get more information about this breakthrough.
Thank you
Juanita mejia
Wendy Sawyer says:

August 11, 2019 at 10:29 pm

Where can I get this done? Also I would be interested in being a volunteer on the missing replacing teeth. I have had several stem cells procedures with 100% success. I live in Southern California
Marilyn Bloch says:

February 1, 2019 at 5:35 am

I would be interested in being a volunteer in this program to test regeneration of teeth
maxine simons says:

January 30, 2019 at 3:16 am

where can I get this done as a volunteer testing in Dallas, Tx.
Shaterra wells says:

January 28, 2019 at 8:09 pm

Where can i get this done
susie says:

January 13, 2018 at 3:11 am

If you need volunteers to test this break through then I am your gal!

To post a reply please login or register

Dental clinic at Columbia University is re-opened

NEW YORK, NY, USA: The Columbia University College of Dental Medicine unveiled its newly renovated Community DentCare School-Based Dental Clinic on 22 May ...

Breakthrough in tooth-tissue engineering announced

NEW YORK, USA/LEIPZIG, Germany: Researchers at the University of Illinois in the US could have discovered the key to re-growing tooth enamel. In a ...

ICOI announces upcoming events through 2024

The International Congress of Oral Implantologists (ICOI) has announced its upcoming events, taking place later this year and extending through 2024. Up ...

Kansas City University breaks ground on College of Dental Medicine

KANSAS CITY, Mo., USA: Kansas City University (KCU), with a 105-year history of improving the well-being of the communities it serves, held a ceremonial ...

Grant from Delta Dental funds Columbia University mobile care unit

NEW YORK, N.Y., USA: The Delta Dental Community Care Foundation recently announced it has awarded Columbia University College of Dental Medicine (CDM) a ...

University of New England announces scholarship in memory of James B. Hanley

PORTLAND, Maine, USA: The University of New England community was deeply saddened by the death of James B. Hanley, DMD, dean of the College of Dental ...

DENTSPLY Tulsa announces winners of GuttaCore University Challenge

Tulsa, Okla., USA: DENTSPLY Tulsa Dental Specialties has announced the winners of its GuttaCore University Challenge. The contest, which began on April 1, ...

Simplifeye announces inaugural AMPLIFY conference for ‘Practice Growth Through Innovation’

Simplifeye, a provider of patient communication and dental practice workflow solutions, has announced it will host its inaugural AMPLIFY conference from May...

AMD LASERS announces booth presence at CDA spring 2012 in Anaheim

Indianapolis, IN, USA: AMD LASERS, a global leader in affordable dental lasers and dental laser education, has announced a new booth presence at the ...

KaVo Kerr Group imaging brands announce second 3D University

Registration is open for the second 3D University (3DU), hosted by KaVo Kerr Group imaging brands Gendex, NOMAD, SOREDEX and Instrumentarium. 3DU is a ...

Education

Live webinar
Mon. 27 January 2025
12:30 PM EST (New York)