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Non-invasive caries management: vVARDIS in the context of global sustainable oral healthcare

Non-invasive biomimetic treatment for early caries may offer a route from guidelines to equitable delivery. (Image: Andrei/Adobe Stock)

Wed. 18 February 2026

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ZUG, Switzerland: Late last year, the World Health Organization released a guideline on preventing and managing caries. The document forms part of the implementation guidance on its Global Strategy and Action Plan on Oral Health 2023–2030, in which the agency sets country targets for environmentally sound dentistry—including implementing measures to phase down amalgam. The document addresses caries as a major global health challenge and provides recommendations on prevention, minimum intervention oral care and the responsible use of resources within oral healthcare systems.

A key implementation challenge is how early caries management is financed and delivered in routine practice. A recent analysis on this issue takes up this point, arguing that conventional approaches to caries management must be reassessed if prevention and early lesion management are to be achieved equitably and pointing to the disconnect between advocacy, education and everyday practice.1 In this context, the authors highlight that non-invasive and biomimetic technologies that target early, non-cavitated carious lesions offer a solution. One example is self-assembling peptide technology used in Curodont Repair, produced by Swiss healthcare company vVARDIS.

“At vVARDIS, we focus on developing biomimetic, non-invasive, drill-free technologies to treat tooth decay,” said Dr Haley Abivardi, co-founder and co-CEO of the company. “Curodont Repair is based on a proprietary formulation which helps restoring tooth structure to its original healthy state, using minerals from the saliva without the need for drilling,” she explained.

“The technology is the result of more than 25 years of research and has been evaluated in randomised controlled trials, long-term clinical studies and meta-analyses.2–6 These studies have demonstrated its safety and clinical performance in the management of early carious lesions,” said Dr Goly Abivardi, co-founder and co-CEO of vVARDIS.

The guideline reflects a broader shift in dentistry towards treatment that is less invasive and more focused on prevention, aligned with public health goals, health system resilience and environmental considerations.7 This involves a move away from intervention-focused restorative approaches towards strategies that prioritise early intervention, preservation of dental tissue and long-term oral health.

Editorial note:

The complete list of references can be found here.

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