Dental News - Colgate touts findings of independent review

Sierra Rendon, DTA

Mon. 3 March 2014

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CHICAGO, Ill., USA: During the Midwinter Meeting, a trio of Colgate executives gathered to announce the positive findings of an independent review on the triclosan/copolymer formula in Colgate Total toothpaste. “I am pleased to confirm that one of our most noteworthy contributions to helping to combat (periodontitis) is our introduction of the triclosan/copolymer system to fluoride toothpaste, which is found in our line of Colgate Total toothpastes,” said Dr. Fotinos S. Panagakos, global director, scientific affairs and research relations, for the Colgate-Palmolive Co.

Panagakos, along with Gavin du Toit, marketing director for Colgate Oral Pharmaceuticals, and Robert A. Faiella, DMD, immediate past president of the American Dental Association, were on hand at the meeting to answer questions about the Colgate Total formula and the independent review.

The review was conducted by the Cochrane Oral Health Group, which carries out systematic reviews of primary research in human health care and health policy that are internationally recognized as the highest standard in evidence-based health care.

Titled “Triclosan/copolymer-containing toothpastes for oral health,” the Cochrane Review evaluated the effects of triclosan/copolymer-containing fluoride toothpastes, as compared with traditional fluoride toothpastes, for the long-term control of caries, plaque and gingivitis in both children and adults.

The Cochrane Review evaluated 30 studies dating from 1990 to 2012 in which 14,835 participants were randomized to receive either a triclosan/copolymer-containing fluoride toothpaste or a traditional fluoride toothpaste that did not contain triclosan/copolymer.

The toothpaste used in the studies containing the triclosan/copolymer system and fluoride was Colgate Total.

The resulting data highlighted the many clinical benefits of using a triclosan/copolymer-containing fluoride toothpaste and concluded there was no evidence of harmful effects associated with the use of triclosan/copolymer toothpastes.

Some key findings of the Cochrane Review include:

After six or more months of use, fluoride toothpaste containing triclosan/copolymer provided a 22 percent reduction in plaque as compared with traditional fluoride toothpaste. It also provided a 41 percent reduction in plaque severity as compared with traditional fluoride toothpaste.
After six or more months of use, fluoride toothpaste containing triclosan/copolymer provided a 22 percent reduction in gingivitis compared with traditional fluoride toothpaste. It provided a 48 percent reduction in gum bleeding compared with traditional fluoride toothpaste.

“I commend the Cochrane Oral Health Group for taking the time to conduct a rigorous review of the clinical studies performed on the fluoride toothpaste containing triclosan/copolymer,” Panagakos said. “I have no doubt that this noteworthy review will draw further attention to the topic of gum disease, which is a prevalent oral health issue. ...”

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