The company reached a valuation of over US$1 billion following Apollo’s investment. Looking back at the company’s development, what were the key business milestones that enabled vVARDIS to reach this point?
Dr Haley Abivardi: Several milestones were critical. First was the recognition of Curodont Repair and Curodont Repair Fluoride Plus in the US as non-invasive restorative treatments, distinct from preventive products such as fluoride varnish. Curodont enables dental professionals to treat early carious lesions through the formation of new hydroxyapatite crystals throughout the lesion, in just a few minutes, without numbing, drilling or artificial restorative material.
Curodont closes a long-standing treatment gap. Fluoride varnish works superficially, but early lesions can extend much deeper. In the past, dentists either watched and waited or removed carious tissue, often sacrificing healthy tooth structure. Now, for the first time, we can regenerate hydroxyapatite throughout the lesion, even in lesions extending toward the amelodentinal junction.
Curodont has created a new category in dentistry. It is backed by over 25 years of research, more than ten years of clinical use, more than 250 scientific publications, peer-reviewed meta-analyses, long-term real-world studies, and a documented success rate above 90%. It is being established as a new standard of care for early-stage caries in renowned universities around the world.
Another key milestone has been rapid adoption. Curodont is the fastest-growing dental product in its category. In the US, it is now used in nearly 20% of dental offices, just over two years since launch. More than three million teeth have been treated in the US and Europe, at a treatment cost per tooth similar to the cost of treating a filling. This momentum has also been recognised by leaders in health care and finance, including by Jamie Dimon at the 2025 J.P. Morgan Healthcare Conference.
Apollo’s investment follows last year’s US$85 million investment by OrbiMed. How has vVARDIS’s funding strategy evolved, and what will this new backing enable the company to do next?
Dr Goly Abivardi: Our funding strategy has focused on partnering with long-term investors who share our vision of transforming dentistry through innovation. OrbiMed supported our global commercial expansion, and Apollo enables the next phase of growth. With Apollo’s backing, we can accelerate the global rollout of Curodont, strengthen our commercial foundation, expand distribution and continue investing in innovation, clinical research and non-invasive, environmentally sustainable oral health care.
Which markets, partnerships or distribution channels have been most important in scaling vVARDIS so far, and where do you see the greatest growth potential now?
Dr Haley Abivardi: The US has been a major growth driver, with adoption across both single-office practices and DSOs, including Heartland Dental, Aspen Dental and PDS Health. Our expanded partnership with Henry Schein continues to accelerate US distribution. In Europe, our partnership with Dental Beauty Partners and mydentist is making Curodont Repair available to more than 500 practices and 3,500 clinicians across the UK. We are also growing in Italy through the Curodont Training Academy.
Looking ahead, we see significant growth potential in the Americas and the Middle East. As clinical guidelines and patient demand shift towards tooth-preserving care, interest in non-invasive restorative solutions such as Curodont Repair continues to grow worldwide.
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